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Found 12 of ic50 for monomerid = 185591
TargetRAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  5nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  7nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  7nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  10nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  10nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  23nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  23nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  44nMAssay Description:As such, the compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profili...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  44nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against FMS, DDR1 and DDR2 kinases using Kinase Screening and Profiling Servic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  56nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [409-765](Homo sapiens (Human))
Hanmi Pharm.

US Patent
LigandPNGBDBM185591(US9156852, 116 | USRE47451, Example 116)
Affinity DataIC50:  56nMAssay Description:The compounds prepared in Examples were tested for inhibitory activity against three subtypes of RAF, i.e., RAF1 Y340D Y341D (C-RAF), B-RAF normal ty...More data for this Ligand-Target Pair