Affinity DataIC50: 0.75nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.840nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.920nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.03nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.05nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.23nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Praecis Pharmaceuticals
Curated by ChEMBL
Praecis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair