Affinity DataKi: 51nMAssay Description:Binding affinity to RORc (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Binding affinity to RORc (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 111nMAssay Description:Binding affinity to RORc-LBD (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 132nMAssay Description:Binding affinity to RORa (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 172nMAssay Description:Binding affinity to RORa-LBD (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Consumable Supplier and product code GFB Unifilter plates Perkin Elmer 6005177 3-[(3- Sigma C5070 Cholamidopropyl)dimethylammonio]- 1-propanesulfonat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of LDHA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Assays were carried out in 16-microL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair