BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50507816(Bms-986165 | Deucravacitinib)

Ki: 0.0200nMAssay Description:Inhibition of fluorescein labeled probe binding to His-tagged human TYK2 pseudokinase domain (575-869 residues) by Morrison titration based HTRF assa...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527158(CHEMBL4476366)

Ki: 40nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527145(CHEMBL4460705)

Ki: 60nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527154(CHEMBL4454255)

Ki: 90nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527152(CHEMBL4573064)

Ki: 170nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527152(CHEMBL4573064)

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527149(CHEMBL4565963)

Ki: 310nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527146(CHEMBL4538853)

Ki: 430nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527148(CHEMBL4461955)

Ki: 680nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527153(CHEMBL4469948)

Ki: 2.00E+3nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527150(CHEMBL4541973)

Ki: 3.40E+3nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527157(CHEMBL4452801)

Ki: 3.70E+3nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527160(CHEMBL4475105)

Ki: 4.40E+3nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527144(CHEMBL4587557)

Ki: 1.53E+4nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Oligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
University Of Karachi

Curated by ChEMBL

BDBM50018905(2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridi...)

Ki: 2.50E+4nMAssay Description:Non-competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15...More data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527156(CHEMBL4551451)

Ki: >4.00E+4nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527147(CHEMBL4592796)

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527151(CHEMBL4440179)

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527155(CHEMBL4439901)

Ki: >5.30E+4nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

Integrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50527159(CHEMBL4560817)

Ki: 6.70E+4nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Oligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
University Of Karachi

Curated by ChEMBL

BDBM50074020(CHEMBL1099206)

Ki: 6.80E+4nMAssay Description:Competitive inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl alpha-D-glucopyranoside as substrate preincubated for 15 min...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565986(CHEMBL4789639)

IC50: 0.190nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50507816(Bms-986165 | Deucravacitinib)

IC50: 0.200nMAssay Description:Allosteric inhibition of fluorescein labeled probe binding to His-tagged recombinant human TYK2 pseudokinase JH2 domain (575-869 residues) incubated ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50507816(Bms-986165 | Deucravacitinib)

IC50: 0.200nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565972(CHEMBL4795231)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565980(CHEMBL4785512)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565974(CHEMBL4800399)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565982(CHEMBL4792694)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565978(CHEMBL4777528)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565971(CHEMBL4792231)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565968(CHEMBL4799019)

IC50: 0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565987(CHEMBL4793760)

IC50: 0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565983(CHEMBL4789015)

IC50: <0.25nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565984(CHEMBL4780233)

IC50: 0.270nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565977(CHEMBL4799559)

IC50: 0.300nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50267796(CHEMBL4098840)

IC50: 0.400nMAssay Description:Inhibition of JAK3 (unknown origin) using CSKtide as substrate after 30 mins in presence of [gamma33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50267827(CHEMBL4076794)

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50267826(CHEMBL4096145)

IC50: 0.400nMAssay Description:Inhibition of GST-tagged JAK1 (unknown origin) after 3 hrs by Caliper assayMore data for this Ligand-Target Pair

PC cid PC sid PDB Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565973(CHEMBL4777175)

IC50: 0.440nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565979(CHEMBL4796821)

IC50: 0.480nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM500292(US11021475, Example 70)

IC50: 0.480nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50267804(CHEMBL4070136)

IC50: 0.5nMAssay Description:Inhibition of JAK3 (unknown origin) using CSKtide as substrate after 30 mins in presence of [gamma33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM500294(US11021475, Example 75)

IC50: 0.5nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase Yes(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research

Curated by ChEMBL

BDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)

IC50: 0.5nMAssay Description:Inhibition of Yes1 (unknown origin) assessed as kinase-dependent enzymatic production of ADP from ATP using coupled luminescence-based reaction by AD...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
MMDB
PDB

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM50267806(CHEMBL4071255)

IC50: 0.5nMAssay Description:Inhibition of GST-tagged JAK1 (unknown origin) after 3 hrs by Caliper assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565975(CHEMBL4784838)

IC50: 0.510nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565976(CHEMBL4792780)

IC50: 0.520nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL

BDBM50565985(CHEMBL4780315)

IC50: 0.540nMAssay Description:Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL

BDBM141473(US8921368, 192)

IC50: 0.600nMAssay Description:Inhibition of JAK3 (unknown origin) using CSKtide as substrate after 30 mins in presence of [gamma33P]ATP by liquid scintillation counting methodMore data for this Ligand-Target Pair