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Found 359 with Last Name = 'chennamaneni' and Initial = 'lr'
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375523(4-(6-(4-(4-(dimethylamino)piperidine-1-carbonyl)ph...)
Affinity DataIC50:  9nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375523(4-(6-(4-(4-(dimethylamino)piperidine-1-carbonyl)ph...)
Affinity DataIC50:  11nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375525(4-(6-(4-(piperazine-1-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375513((4-(3-(4-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375522(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375513((4-(3-(4-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375525(4-(6-(4-(piperazine-1-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455538(CHEMBL4214092)
Affinity DataIC50:  31nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375522(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM50455538(CHEMBL4214092)
Affinity DataIC50:  60nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  64nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50:  72nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50:  84nMAssay Description:Inhibition of GST-tagged MNK1 (37 to 341 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50:  86nMAssay Description:Inhibition of GST-tagged MNK2 (72 to 385 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using JH3 peptide as substrate preincubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375537(N-(5-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-y...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375537(N-(5-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-y...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375538(5-(6-(4-(4-methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375538(5-(6-(4-(4-methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375539((4-(3-(1H-indazol-5-yl)imidazo[1,2-b]pyridazin-6-y...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375539((4-(3-(1H-indazol-5-yl)imidazo[1,2-b]pyridazin-6-y...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375540((4-(3-(1H-benzo[d]imidazol-5-yl)imidazo[1,2-b]pyri...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375540((4-(3-(1H-benzo[d]imidazol-5-yl)imidazo[1,2-b]pyri...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375541(5-(6-(4-(4-(4-methylpiperazin-1-yl)piperidine-1-ca...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375541(5-(6-(4-(4-(4-methylpiperazin-1-yl)piperidine-1-ca...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375542(5-(6-(4-(4-morpholinopiperidine-1-carbonyl)phenyl)...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375542(5-(6-(4-(4-morpholinopiperidine-1-carbonyl)phenyl)...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375543(4-(6-(4-(4-Methylpiperazine-1-carbonyl)phenyl)imid...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375544(4-(6-(4-(morpholine-4-carbonyl)phenyl)imidazo[1,2-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375546(4-(6-(4-(1,4-oxazepane-4-carbonyl)phenyl imidazo[1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375546(4-(6-(4-(1,4-oxazepane-4-carbonyl)phenyl imidazo[1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375547(4-(6-(4-(4-ethylpiperazine-1-carbonyl)phenyl)imida...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375547(4-(6-(4-(4-ethylpiperazine-1-carbonyl)phenyl)imida...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375548(N-(1-(4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375548(N-(1-(4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375549(4-(6-(4-(4-(diethylamino)-4-methylpiperidine-1-car...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375549(4-(6-(4-(4-(diethylamino)-4-methylpiperidine-1-car...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375550(4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-N-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375550(4-(3-(4-cyanophenyl)imidazo[1,2-a]pyridin-6-yl)-N-...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375551(4-(6-(4-(3-oxopiperazine-1-carbonyl)phenyl)imidazo...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375551(4-(6-(4-(3-oxopiperazine-1-carbonyl)phenyl)imidazo...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375552(4-(6-(4-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375552(4-(6-(4-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375553(4-(6-(4-(1′-methyl-4,4′-bipiperidine-1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375553(4-(6-(4-(1′-methyl-4,4′-bipiperidine-1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375554(4-(6-(4-(4-hydroxy-4-methylpiperidine-1-carbonyl)p...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375554(4-(6-(4-(4-hydroxy-4-methylpiperidine-1-carbonyl)p...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375555(4-(6-(4-(1,4-diazepane-1-carbonyl)phenyl)imidazo[1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Agency For Science, Technology And Research (A*Star)

Curated by ChEMBL
LigandPNGBDBM375555(4-(6-(4-(1,4-diazepane-1-carbonyl)phenyl)imidazo[1...)
Affinity DataIC50: <100nMAssay Description:MNK1 and MNK2 inhibitor activity was determined using recombinant kinase domains expressed in E. coli. MNK1 and MNK2 were expressed as GST fusion pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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