Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 50012012
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113332(3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-t...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50095027((2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-eth...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor in humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113325((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  0.510nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113330((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  0.910nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113333((4-Nitro-phenyl)-(1-phenethyl-piperidin-4-yl)-meth...)
Affinity DataKi:  1.15nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113329((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  1.63nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  1.95nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113324((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  3.62nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  3.68nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113324((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  7.32nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113325((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  8.76nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113339((4-Nitro-phenyl)-(1-phenethyl-piperidin-4-yl)-meth...)
Affinity DataKi:  9.34nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  9.54nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113328((4-Fluoro-phenyl)-[1-(3-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi:  12.7nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113340((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  13.1nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113325((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  16.6nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113330((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  28.6nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113337((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  32.1nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  35.5nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113325((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  48.9nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113325((4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  51.8nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  63nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113330((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  101nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113331((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  138nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113324((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  144nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113324((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  176nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113338((4-Fluoro-phenyl)-[1-(2-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi:  191nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113336((4-Fluoro-phenyl)-[1-(4-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi:  227nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113324((4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  300nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113330((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi:  430nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  453nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  493nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113329((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  503nMAssay Description:Tested on transfected cell membranes selectively expressing human 5-hydroxytryptamine 2C receptor using [3H]-mesulergineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113329((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  1.35E+3nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 7 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113326((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi:  3.00E+3nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113334((4-Fluoro-phenyl)-[1-(3-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113329((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113327((4-Fluoro-phenyl)-[1-(2-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113335((4-Fluoro-phenyl)-[1-(4-iodo-benzyl)-piperidin-4-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested on genetically transfected COS7 cell membranes selectively expressing human 5-hydroxytryptamine 2A receptor, using [3H]-ketanserin as radiolig...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113329((4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested on cell membranes from transfected cells selectively expressing human 5-hydroxytryptamine 6 receptor incubated with 1 nM [3H]-LSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Yale University

Curated by ChEMBL
LigandPNGBDBM50113330((4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity (Ki) at Dopamine receptor D2 using rat caudate cells with nemonapride (0.075 nM) as a radioligand and 10 M haloperidol as a blank ag...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed