BDBM10480 A4A.2HCl::Bis-THA inhibitor 3::CHEMBL211313::N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]-1,2,3,4-tetrahydroacridin-9-amine dihydrochloride

SMILES C(CCNc1c2CCCCc2nc2ccccc12)CNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=RUTSCXRBSZSXSL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10480   

TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)
Affinity DataIC50:  157nMpH: 7.4 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarboxylic ester hydrolase(Rat)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)
Affinity DataIC50:  252nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Rat)
Hong Kong University of Science and Technology

LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)
Affinity DataIC50:  157nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCarboxylic ester hydrolase(Rat)
Institute of Science

Curated by ChEMBL
LigandPNGBDBM10480(A4A.2HCl | Bis-THA inhibitor 3 | CHEMBL211313 | N-...)
Affinity DataIC50:  252nMpH: 7.4 T: 37°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed