BindingDB is a public, web-accessible database of measured binding affinities, focusing chiefly on the interactions of protein considered to be drug-targets with small, drug-like molecules. As of June 13, 2021, BindingDB contains 41,300 Entries, each with a DOI, containing 2,286,319 binding data for 8,536 protein targets and 989,383 small molecules.
There are 2823 protein-ligand crystal structures with BindingDB affinity measurements for proteins with 100% sequence identity, and 8263 crystal structures allowing proteins to 85% sequence identity.
We are excited to share our new browser extension, BDBFind. Once installed in your browser, BDBFind automatically lets you know when BindingDB has the data from an article, PubMed Entry, or US Patent you are looking at online and provides direct links to view or download the data. Get BDBFind by searching for it in the Chrome webstore or in Firefox extensions or by following these links:
BindingDB curates US Patents. We have scanned patents back to 2013 for suitable data and are currently up to date as of mid-2020. However, we cannot be sure of capturing all relevant patents, so if you know of a useful one we have missed, please let us know and we will try to curate it. As of June 13, 2021, BindingDB's patent dataset comprises:
Binding measurements: 717,847
Target proteins: 2,059
Average Number of Targets per Patent: 1.91
Journal Curation by BindingDB
BindingDB continually curates a set of journals not covered by other public databases. As of June 13, 2021, the status of our current curation effort is as follows: