BDBM16099 3-carbamoyl-5-(4-phenylphenyl)benzoic acid::5-carbamoyl-1,1 :4 ,1 -terphenyl-3-carboxylic acid::AMX02::Brequinar-derived asymmetric terphenyl compound

SMILES: NC(=O)c1cc(cc(c1)-c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key: InChIKey=LAZPCGBRHLARSI-UHFFFAOYSA-N

Data: 1 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Homo sapiens (Human))	BDBM16099 (3-carbamoyl-5-(4-phenylphenyl)benzoic acid | 5-car...) Show SMILES NC(=O)c1cc(cc(c1)-c1ccc(cc1)-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H15NO3/c21-19(22)17-10-16(11-18(12-17)20(23)24)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12H,(H2,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	2.80E+3	-7.49	n/a	n/a	n/a	n/a	n/a	8.0	22
Cornell University					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				Bioorg Med Chem Lett 16: 1610-5 (2006)
					More data for this Ligand-Target Pair				3D Structure (crystal)