BDBM18163 4-[(1R,6R,7S)-3,5-dioxo-2,4-diazatricyclo[5.2.1.0^{2,6}]decan-4-yl]naphthalene-1-carbonitrile::N-aryl-bicyclic hydantoin, 4b

SMILES Oc1c2[C@H]3CC[C@H](C3)n2c(=O)n1-c1ccc(C#N)c2ccccc12

InChI Key InChIKey=ZBVCEGCGGLIGHI-WCQYABFASA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18163   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM18163(4-[(1R,6R,7S)-3,5-dioxo-2,4-diazatricyclo[5.2.1.0^...)
Affinity DataKi:  24nM ΔG°:  -10.3kcal/mole IC50:  260nM EC50: >1.00E+3nMpH: 7.4 T: 22°CAssay Description:Receptor Binding Assay (Ki)-Binding determined through direct displacement of ligand with [3H]-DHT in the MDA-453 cell line. Transactivation Assay (E...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed