BDBM21170 1-[2-(2,4-dichlorophenoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole::Imidazole-based ligand, 21

SMILES Clc1ccc(OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1

InChI Key InChIKey=ZSEJKLXYMYILHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21170   

TargetCytochrome P450 2C9(Human)
Astrazeneca

LigandPNGBDBM21170(1-[2-(2,4-dichlorophenoxy)-2-(2,4-dichlorophenyl)e...)
Affinity DataIC50:  1.00E+4nMAssay Description:The inhibition of recombinant human CYP2C9 was measured as the ability to perform a demethylation of 7-methoxy-4-trifluoromethylcoumarin (MFC). Befor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

LigandPNGBDBM21170(1-[2-(2,4-dichlorophenoxy)-2-(2,4-dichlorophenyl)e...)
Affinity DataIC50:  60nMpH: 7.4 T: 37°CAssay Description:The inhibition of recombinant human CYP3A4 was measured as the ability to perform a debenzylation of 7-benzyloxy-4-trifluoromethylcoumarin (BFC). Bef...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed