BDBM21771 2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 17r

SMILES CCc1ccc(OCCCOc2ccc3[C@H](CC(O)=O)CCc3c2)c(OC)c1

InChI Key InChIKey=RBIDPFUSXWXMEN-SFHVURJKSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 21771   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  700nMpH: 7.4 T: 22°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  2.70nMT: 25°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  6.17E+5nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  3.70E+8nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  1.43E+6nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARalpha ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM21771(2-[(1S)-5-[3-(4-ethyl-2-methoxyphenoxy)propoxy]-2,...)
Affinity DataEC50:  1.65E+3nMT: 25°CAssay Description:PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed