BDBM22754 1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione::Benzil-based compound, 32

SMILES Oc1ccc(C(=O)C(=O)c2ccc(O)cc2O)c(O)c1

InChI Key InChIKey=NGWYJYHAFLMHNW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22754   

TargetCoagulation factor XII(Human)
University of Mississippi

LigandPNGBDBM22754(1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione | Ben...)
Affinity DataKi:  1.73E+3nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Human)
University of Mississippi

LigandPNGBDBM22754(1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione | Ben...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Human)
University of Mississippi

LigandPNGBDBM22754(1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione | Ben...)
Affinity DataKi: >1.00E+5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Estimates of the competitive inhibition constants (Ki) were ob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Human)
University of Mississippi

LigandPNGBDBM22754(1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione | Ben...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Rabbit)
University of Mississippi

LigandPNGBDBM22754(1,2-bis(2,4-dihydroxyphenyl)ethane-1,2-dione | Ben...)
Affinity DataKi: >1.00E+5nMAssay Description:CE inhibition was determined using a spectrophotometric multiwell plate assay with o-NPA as a substrate. The rate of change in absorbance at 420 nm w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed