BDBM22915 3-(1H-imidazol-4-yl)propylphenylmethyl ether::5-[3-(benzyloxy)propyl]-1H-imidazole::CHEMBL61618::Proxyfan

SMILES C(COCc1ccccc1)Cc1cnc[nH]1

InChI Key InChIKey=WNWALBVQAAIULR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 22915   

TargetHistamine H3 receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22915(3-(1H-imidazol-4-yl)propylphenylmethyl ether | 5-[...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of [125I]-iodoproxyfan binding to human histamine H3 receptor of CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22915(3-(1H-imidazol-4-yl)propylphenylmethyl ether | 5-[...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22915(3-(1H-imidazol-4-yl)propylphenylmethyl ether | 5-[...)
Affinity DataKi:  13nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Rat)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM22915(3-(1H-imidazol-4-yl)propylphenylmethyl ether | 5-[...)
Affinity DataKi:  20nMAssay Description:In vitro antagonistic activity against histamine H3-receptor in an assay with K+-evoked depolarisation-induced release of [3H]histamine of synaptosom...More data for this Ligand-Target Pair
In DepthDetails Article

TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22915(3-(1H-imidazol-4-yl)propylphenylmethyl ether | 5-[...)
Affinity DataKi:  50nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed