BDBM25754 2-[4-(2-{[(2R)-2-hydroxy-3-phenoxypropyl]amino}ethoxy)phenoxy]acetic acid::ICI 215001

SMILES O[C@H](CNCCOc1ccc(OCC(O)=O)cc1)COc1ccccc1

InChI Key InChIKey=MXWICZOXPUWAHY-OAHLLOKOSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25754   

TargetBeta-1 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25754(2-[4-(2-{[(2R)-2-hydroxy-3-phenoxypropyl]amino}eth...)
Affinity DataKd:  427nMpH: 7.4 T: 37°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25754(2-[4-(2-{[(2R)-2-hydroxy-3-phenoxypropyl]amino}eth...)
Affinity DataKd:  234nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Human)
University of Nottingham

LigandPNGBDBM25754(2-[4-(2-{[(2R)-2-hydroxy-3-phenoxypropyl]amino}eth...)
Affinity DataKd:  1.38E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed