BDBM26892 3-butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 13

SMILES CCCCN1CN(c2ccccc2)C2(CCN(CC2)C(c2ccccc2)c2ccccc2)C1=O

InChI Key InChIKey=VFEHYWWZSNCIAC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26892   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26892(3-butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazasp...)
Affinity DataKi:  57nM ΔG°:  -9.78kcal/molepH: 7.4 T: 22°CAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26892(3-butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazasp...)
Affinity DataKi:  773nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26892(3-butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazasp...)
Affinity DataKi:  8.44E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

LigandPNGBDBM26892(3-butyl-8-(diphenylmethyl)-1-phenyl-1,3,8-triazasp...)
Affinity DataKi:  5.94E+4nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed