BDBM35738 sulfonamide deriv., 7f

SMILES NS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2)c(Br)c1

InChI Key InChIKey=LBFJKAVSXZGFAX-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 35738   

TargetCarbonic anhydrase 7(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  5.30nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  5.90nM ΔG°:  -11.2kcal/moleT: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istanbul University

LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  7.10nM ΔG°:  -11.1kcal/moleT: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  263nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  263nM ΔG°:  -8.97kcal/molepH: 7.4 T: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  395nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35738(sulfonamide deriv., 7f)
Affinity DataKi:  395nM ΔG°:  -8.73kcal/molepH: 7.4 T: 25°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed