BDBM36433 4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamide, 82::CID25105716

SMILES Clc1ccc(cc1)C(=O)N(CCN1CCC2(CC1)N(CNC2=O)c1ccccc1)C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=KIOMHAPZIAUVSW-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 36433   

TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM36433(4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-...)
Affinity DataIC50: >2.00E+4nMT: 37°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM36433(4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-...)
Affinity DataIC50:  2.50E+3nMT: 37°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM36433(4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-...)
Affinity DataEC50:  1.20E+3nMT: 37°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM36433(4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-...)
Affinity DataEC50:  3.40E+3nMT: 37°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Human)
Vanderbilt University

LigandPNGBDBM36433(4-Chloro-N-(4-chlorobenzoyl)-N-(2-(4-oxo-1-phenyl-...)
Affinity DataIC50: >2.00E+4nMT: 37°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed