BDBM46671 2-Phenyl-1,2-dihydro-indazol-3-one::2-phenyl-1H-indazol-3-one::2-phenylindazolin-3-one::CHEMBL412902::MLS-0315919.0001::cid_411519

SMILES O=c1n([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=CFNJFZDGHGYAMU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 46671   

TargetPhosphomannomutase 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46671(2-Phenyl-1,2-dihydro-indazol-3-one | 2-phenyl-1H-i...)
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMannose-6-phosphate isomerase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM46671(2-Phenyl-1,2-dihydro-indazol-3-one | 2-phenyl-1H-i...)
Affinity DataIC50:  4.49E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProstaglandin G/H synthase 1/2(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM46671(2-Phenyl-1,2-dihydro-indazol-3-one | 2-phenyl-1H-i...)
Affinity DataIC50:  2.70E+3nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM46671(2-Phenyl-1,2-dihydro-indazol-3-one | 2-phenyl-1H-i...)
Affinity DataEC50: >4.75E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM46671(2-Phenyl-1,2-dihydro-indazol-3-one | 2-phenyl-1H-i...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed