BDBM49388 7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one::7-benzoxychroman-4-one::7-phenylmethoxy-2,3-dihydrochromen-4-one::7-phenylmethoxy-3,4-dihydro-2H-1-benzopyran-4-one::MLS000594478::SMR000115170::cid_4521898

SMILES O=C1CCOc2cc(OCc3ccccc3)ccc12

InChI Key InChIKey=MLQFOEOUNIRULR-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 49388   

TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50:  824nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50:  168nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu7 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 8(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 3(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu3 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 4(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM49388(7-(benzyloxy)-2,3-dihydro-4H-chromen-4-one | 7-ben...)
Affinity DataEC50:  950nMAssay Description:Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed