BDBM50001260 3-phenyl-4-hydroxyquinolin-2(1H)-one::4-Hydroxy-3-phenyl-1H-quinolin-2-one::4-hydroxy-3-phenylquinolin-2(1H)-one::CHEMBL324519

SMILES Oc1c(-c2ccccc2)c(=O)[nH]c2ccccc12

InChI Key InChIKey=WNISVGSZMGXKHE-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001260   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataKi:  4.50E+3nMAssay Description:Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataIC50:  7.29E+3nMAssay Description:Inhibition of [3H]-MK-801 binding to a N-methyl-D-aspartic acid(NMDA) receptor in glycine-sensitive rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFatty acid synthase(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50001260(3-phenyl-4-hydroxyquinolin-2(1H)-one | 4-Hydroxy-3...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of rat FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed