BDBM50001676 CHEMBL3237776::Mr-I-27

SMILES COc1ccccc1C(=O)NN

InChI Key InChIKey=QMGXWNSSMGAHCA-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50001676   

TargetCathepsin B(Goat)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50001676(CHEMBL3237776 | Mr-I-27)
Affinity DataKi:  1.30E+4nMAssay Description:Competitive inhibition of cathepsin B in goat liver using alpha-N-benzoyl-D,L-arginine-2-naphthylamide as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
University of Karachi

LigandPNGBDBM50001676(CHEMBL3237776 | Mr-I-27)
Affinity DataIC50:  1.50E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50001676(CHEMBL3237776 | Mr-I-27)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
University of Karachi

LigandPNGBDBM50001676(CHEMBL3237776 | Mr-I-27)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human liver cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50001676(CHEMBL3237776 | Mr-I-27)
Affinity DataIC50:  1.65E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed