BDBM50005075 (2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL287327

SMILES OC(=O)[C@H]1C[C@H](NC(=O)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key InChIKey=UCKHICKHGAOGAP-UONOGXRCSA-N

Data  1 KI  3 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50005075   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataKi:  6.30nMAssay Description:Inhibition of [3H]glycine to glycine binding site, associated with the N-methyl-D-aspartate glutamate receptor 1 in crude synaptic membranes prepared...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Glaxo Wellcome

Curated by ChEMBL
LigandPNGBDBM50005075((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...)
Affinity DataIC50:  4nMAssay Description:Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair