BDBM50007082 (E)-2-methoxy-4-(2-nitrovinyl)phenol::2-Methoxy-4-(2-nitro-vinyl)-phenol::2-methoxy-4-(2-nitrovinyl)phenol::CHEMBL309016::cid_638439

SMILES COc1cc(\C=C\[N+]([O-])=O)ccc1O

InChI Key InChIKey=XVXCSPJSXIUNQJ-SNAWJCMRSA-N

Data  11 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50007082   

TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50: >4.60E+3nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetGalanin receptor type 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  1.11E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

Target60S ribosomal protein L19-A(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataEC50:  3.21E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataEC50:  8.18E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetEndothelial PAS domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  1.10E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetBeta-lactamase(Pseudomonas aeruginosa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50: >4.98E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of the epidermal growth factor receptor expressed in A431 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase ABL1/ABL2(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTransitional endoplasmic reticulum ATPase(Human)
California Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of His6-tagged p97 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as reduction in ATPase activity measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50007082((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)
Affinity DataIC50:  4.84E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay