BDBM50010833 CHEMBL552615::CHEMBL99585::Ersentilide::N-(4-{2-Hydroxy-3-[2-(4-imidazol-1-yl-phenoxy)-ethylamino]-propoxy}-phenyl)-methanesulfonamide; hydrochloride::N-[4-(2-Hydroxy-3-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-propoxy)-phenyl]-methanesulfonamide

SMILES CS(=O)(=O)Nc1ccc(OCC(O)CNCCOc2ccc(cc2)-n2ccnc2)cc1

InChI Key InChIKey=QZWUQVSQIFFFKY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50010833   

TargetBeta-2 adrenergic receptor(Dog)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  4.65E+4nMAssay Description:Beta2-receptor selectivity in canine lung tissue in anesthetized dogsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Human)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Human)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  2.40E+3nMAssay Description:Tested for Beta-1 adrenergic receptor selectivity in canine cardiac tissue in anesthetized dogsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Dog)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM50010833(CHEMBL552615 | CHEMBL99585 | Ersentilide | N-(4-{2...)
Affinity DataIC50:  4.70E+4nMAssay Description:In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed