BDBM94503 2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)-4-piperidinyl]-N-phenylpropanamide::2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide::MLS002320668::N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenyl-propanamide;2-oxidanylpropane-1,2,3-tricarboxylic acid::SMR001338814::SUFENTANIL::Sufentanil citrate::Sufentanyl::cid_65494::citric acid;N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenyl-propionamide

SMILES CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2cccs2)CC1

InChI Key InChIKey=GGCSSNBKKAUURC-UHFFFAOYSA-N

Data  6 KI  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 94503   

LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  0.0200nMAssay Description:In vitro affinity to displace [3H]naloxone from opiate receptor in freshly prepared rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMu-type opioid receptor(Rat)
Anaquest Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  0.220nMAssay Description:Ability to displace [3H]-naloxone from the Opioid receptor mu 1 isolated from the rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetDelta-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  50nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetKappa-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataKi:  75nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in human U2OS cells co-transfected with beta-arrestin-2 assessed as increase in beta-arrestin-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMu-type opioid receptor(Human)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membranes after 1 hr by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [3H]nalotrexone from rat-brain Opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  4.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 1(Human)
University Medicine Greifswald

Curated by ChEMBL
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  1.94E+4nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as reduction in ASP+ substrate uptake by microplate reader based analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPerilipin-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  2.09E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  2.48E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-5(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM94503(2-hydroxypropane-1,2,3-tricarboxylic acid;N-[4-(me...)
Affinity DataIC50:  2.71E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay