BDBM50015142 4-Phenylbutyrohydroxamic acid::CHEMBL55895::N-Hydroxy-4-phenyl-butyramide

SMILES ONC(=O)CCCc1ccccc1

InChI Key InChIKey=UPHXPXYRKPCXHK-UHFFFAOYSA-N

Data  13 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50015142   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Rat)
Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  1.50E+4nMAssay Description:Invitro inhibition of rat platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  2.70E+4nMAssay Description:In vitro inhibitory activity against RBL-1 5-LOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  2.69E+4nMAssay Description:Logarithmic value of inhibitory concentration against 5-lipoxygenase in rat basophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  2.70E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  4.30E+5nMAssay Description:Inhibition of human recombinant HDAC9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50015142(4-Phenylbutyrohydroxamic acid | CHEMBL55895 | N-Hy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed