BDBM50014651 2-Methyl-1,2,3,4-tetrahydro-isoquinoline::2-Methyl-1,2,3,4-tetrahydro-isoquinoline; hydrochloride::CHEMBL22053::CHEMBL545413

SMILES CN1CCc2ccccc2C1

InChI Key InChIKey=KYXSVGVQGFPNRQ-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50014651   

TargetAmine oxidase [flavin-containing] B(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataKi:  1.00E+3nMAssay Description:Compounds were tested for inhibition against human liver Monoamine oxidase B (competitive inhibition was observed)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataKi:  1.33E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
University of Texas

Curated by ChEMBL
LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of human placental Monoamine oxidase A (competitive inhibition was observed)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysosomal Pro-X carboxypeptidase(Human)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to phencyclidine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSigma non-opioid intracellular receptor 1(Rat)
G. D. Searle

Curated by ChEMBL
LigandPNGBDBM50014651(2-Methyl-1,2,3,4-tetrahydro-isoquinoline | 2-Methy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of [3H]- N-allylnormetazocine ([3H]NANM) binding to sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed