BDBM50019754 IDALOPIRDINE::LU-AE58054

SMILES FC(F)C(F)(F)COc1cccc(CNCCc2c[nH]c3cc(F)ccc23)c1

InChI Key InChIKey=YBAWYTYNMZWMMJ-UHFFFAOYSA-N

Data  17 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50019754   

Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to 5-HT6R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in CHO cells assessed as inhibition constant incubated for 120 mins by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in CHO cell membranes incubated for 120 mins by scintillation counter methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]Lu AE60157 from rat brain 5-HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Binding affinity to 5HT6R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  0.830nMAssay Description:Antagonist activity at 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-LSD from human 5-HT6R expressed in HEK293 cells after 1 hr by microbeta plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membrane measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]5-HT from 5-HT2C receptor (unknown origin) expressed in hamster AV12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  791nMAssay Description:Binding affinity to human 5-HT2AR expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  1.22E+3nMAssay Description:Displacement of [3H]-raclopride from human D2R expressed in HEK293 cells after 1 hr by microbeta plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  3.94E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells after 1 hr by microbeta plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataKi:  8.64E+3nMAssay Description:Displacement of [3H]-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by microbeta plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at recombinant human 5HT6R expressed in CHO cells assessed as inhibition of 5HT-stimulated cAMP accumulation incubated for 4 hrs ...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(IDALOPIRDINE | LU-AE58054)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in COS-7 cells assessed as inhibition of 5HT-induced cAMP accumulation preincubated for 7 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed