BDBM50024822 1,2,3,4-Tetrahydro-isoquinolin-6-ol::CHEMBL310736

SMILES Oc1ccc2CNCCc2c1

InChI Key InChIKey=SCMZIFSYPJICCV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50024822   

LigandPNGBDBM50024822(1,2,3,4-Tetrahydro-isoquinolin-6-ol | CHEMBL310736)
Affinity DataKi:  2.48E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50024822(1,2,3,4-Tetrahydro-isoquinolin-6-ol | CHEMBL310736)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50024822(1,2,3,4-Tetrahydro-isoquinolin-6-ol | CHEMBL310736)
Affinity DataKi:  7.80E+3nMAssay Description:In vitro inhibition of bovine phenylethylamine N-methyl-transferase (PNMT) using radiochemical assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed