BDBM81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-)

SMILES CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C

InChI Key InChIKey=OZVBMTJYIDMWIL-AYFBDAFISA-N

Data  67 KI  8 IC50  4 Kd  2 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 81 hits for monomerid = 81993   

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  0.620nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank
PDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Mouse)
Medical Research Service

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  0.690nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetAlpha-1D adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  1.12nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-1B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  1.38nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetD(2) dopamine receptor(Bovine)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetAlpha-1A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  4.17nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  6.76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  7.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetD(3) dopamine receptor(Rat)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  7.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  8.20nMMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank
PDB3D3D Structure (crystal)

LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
In DepthDetails PubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacement of [3H]-U-86,170.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1D(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  10.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  11.0nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  12.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  14.8nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  15nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  19nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards Serotonin 5-hydroxytryptamine 1A receptor by displacement of [3H]-(+)-8-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  25nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  28.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
University of Washington

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  33nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  34.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  48.8nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  49.0nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  54nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 2B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  56.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetAlpha-2A adrenergic receptor [16-465](Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  67.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  68nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  83nMMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetD(3) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  87nMAssay Description:Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  107nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  110nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
PDB3D3D Structure (crystal)

Target5-hydroxytryptamine receptor 2A(Rat)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  117nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

Target5-hydroxytryptamine receptor 7(Mouse)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetD(4) dopamine receptor(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  285nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetD(4) dopamine receptor(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  340nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM81993(BROMOCRIPTINE | Bromocriptine+ (GTP+) | Bromocript...)
Affinity DataKi:  355nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


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