BDBM50030172 CHEMBL3343526

SMILES NC(=O)c1cncc(Sc2ccc3ccccc3c2)c1

InChI Key InChIKey=PNZKIFUFRJYJPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030172   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030172(CHEMBL3343526)
Affinity DataIC50:  2.79E+4nMAssay Description:Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030172(CHEMBL3343526)
Affinity DataIC50:  2.69E+4nMAssay Description:Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50030172(CHEMBL3343526)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed