BDBM50030279 2-Amino-5-(N'-methyl-guanidino)-pentanoic acid::CHEMBL312870

SMILES CNC(=N)NCCCC(N)C(O)=O

InChI Key InChIKey=NTNWOCRCBQPEKQ-UHFFFAOYSA-N

Data  3 KI  8 IC50

PDB links: 31 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50030279   

TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataKi:  5.90E+3nMAssay Description:Compound was tested for binding affinity against Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataKi:  1.00E+4nMAssay Description:Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataKi:  1.40E+4nMAssay Description:Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against human neuronal nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Rat)
G. D. Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  1.80E+4nMAssay Description:Tested for inhibition of rat brain inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against human endothelial nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity of compound against human inducible nitiric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, brain(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  890nMAssay Description:Concentration required to inhibit neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of inducible nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  540nMAssay Description:In vitro inhibition of endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50030279(2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)
Affinity DataIC50:  8.30E+3nMAssay Description:Tested for inhibition of mouse inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed