BDBM50031472 1,2,3-Trihydroxybenzene, XIV::CHEMBL307145::Pyrogallol (10)::benzene-1,2,3-triol::pyrogallol

SMILES Oc1cccc(O)c1O

InChI Key InChIKey=WQGWDDDVZFFDIG-UHFFFAOYSA-N

Data  15 KI  4 IC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50031472   

TargetCarbonic anhydrase 4(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  490nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Human)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  520nMAssay Description:Inhibition of human CA6 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  520nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  540nMAssay Description:Inhibition of human CA2 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  2.03E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  3.63E+3nMAssay Description:Inhibition of ADAMTS-5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  3.89E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase(European seabass)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  4.39E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  4.43E+3nMAssay Description:Inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  6.34E+3nMAssay Description:Inhibition of ADAMTS-4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 6(Human)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  6.83E+3nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  7.35E+3nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  7.41E+3nMAssay Description:Inhibition of human CA1 using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-lipoxygenase(Bovine)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataIC50:  4.00E+3nMAssay Description:5-LO inhibitory activity was determined by inhibition of LTB4 biosynthesis in bovine polymorphonuclear leukocytes (PMNL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rat)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of rat intestinal sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50031472(1,2,3-Trihydroxybenzene, XIV | CHEMBL307145 | Pyro...)
Affinity DataIC50:  1.44E+5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed