BDBM50031936 6-(4-Methyl-piperazin-1-yl)-7-oxa-5-aza-benzo[c]fluorene::CHEMBL293866

SMILES CN1CCN(CC1)c1nc2ccccc2c2c3ccccc3oc12

InChI Key InChIKey=AXXBKGLWQLKREC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031936   

Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031936(6-(4-Methyl-piperazin-1-yl)-7-oxa-5-aza-benzo[c]fl...)
Affinity DataKi:  13nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031936(6-(4-Methyl-piperazin-1-yl)-7-oxa-5-aza-benzo[c]fl...)
Affinity DataKi:  13nMAssay Description:Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031936(6-(4-Methyl-piperazin-1-yl)-7-oxa-5-aza-benzo[c]fl...)
Affinity DataKi:  450nMAssay Description:Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50031936(6-(4-Methyl-piperazin-1-yl)-7-oxa-5-aza-benzo[c]fl...)
Affinity DataKi:  6.90E+3nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 4 receptor from guinea pig striatum using [3H]GR-113808 as radioligand...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed