BDBM50033324 (3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine::CHEMBL118812

SMILES [O-][N+](=O)c1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=KBEUKMLEXDGSBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50033324   

LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against phosphodiesterase 5 from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human GFP-fused ABCG2 expressed in MDCK2 cells assessed as reduction in Hoechst 33342 efflux preincubated for 30 mins followed by Hoech...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50033324((3-Nitro-phenyl)-(2-phenyl-quinazolin-4-yl)-amine ...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells preincubated for 30 mins prior to Hoechst 33342 addition measured every 60 secs up to 120 mins by H...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed