BDBM50037038 2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-benzothiazol-6-ol::CHEMBL105587

SMILES CCNc1nc2c(C)c(Cc3cccnc3)c(O)c(C)c2s1

InChI Key InChIKey=JRQGTFOVYZJVQO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037038   

TargetThromboxane-A synthase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  390nMAssay Description:Tested for inhibitory activity against thromboxane A2 (TXA2) synthetase in microsome of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against the production of leukotriene B4 (LTB4) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetThromboxane-A synthase(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50037038(2-Ethylamino-4,7-dimethyl-5-pyridin-3-ylmethyl-ben...)
Affinity DataIC50:  650nMAssay Description:Inhibitory activity against the production of thromboxane B2 (TXB2) in glycogen-induced peritoneal cells of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed