BDBM50037469 (6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL115917

SMILES C[C@H]1C2Cc3ccc(O)cc3[C@@]1(C)CCN2C

InChI Key InChIKey=YGSVZRIZCHZUHB-WAJWKUKPSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50037469   

TargetMu-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037469((6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  4.20nMAssay Description:Inhibition against mu receptor from displacement studies using 0.5 nM [3H]-DAMGO in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037469((6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  11nMAssay Description:Inhibition against mu receptor using [3H]DAMGO in homogenate of rat brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037469((6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  17nMAssay Description:Inhibition against kappa receptor from displacement studies using 1.5 nM [3H]U-69593 in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037469((6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  152nMAssay Description:Inhibition against delta receptor from displacement studies using 1.5 nM [3H]DPDPE in rhesus monkey cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50037469((6S,11R)-3,6,11-Trimethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataKi:  1.81E+4nMAssay Description:Inhibition against sigma receptor using displacement of 3 nM [3H]pentazocine in homogenate of guinea pig brain cerebellumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed