BDBM50039091 (Z)-3-(3,4-Dimethoxy-phenyl)-2-pyridin-3-yl-acrylonitrile::CHEMBL67027::RG-13022

SMILES COc1ccc(\C=C(/C#N)c2cccnc2)cc1OC

InChI Key InChIKey=DBGZNJVTHYFQJI-RIYZIHGNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50039091   

TargetEpidermal growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039091((Z)-3-(3,4-Dimethoxy-phenyl)-2-pyridin-3-yl-acrylo...)
Affinity DataIC50:  700nMAssay Description:Concentration required to inhibit phosphorylation of isolated human epidermal growth factor tyrosine kinase receptor by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-derived growth factor receptor alpha/beta(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50039091((Z)-3-(3,4-Dimethoxy-phenyl)-2-pyridin-3-yl-acrylo...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human PDGF receptor phosphorylation; 0.5-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed