BDBM50044009 CHEMBL3356427

SMILES CN(C)C(=O)Oc1cccc(NC(=O)C2(C)CCN(CC2)c2ncnc3[nH]cc(C)c23)c1

InChI Key InChIKey=NDUMDYQFHRPXEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044009   

TargetLIM domain kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50044009(CHEMBL3356427)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of LIMK2 (unknown origin) in presence of ATP at 25 uMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 2(Human)
Universita Degli Studi Di Siena

Curated by ChEMBL
LigandPNGBDBM50044009(CHEMBL3356427)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human full-length LIMK2 assessed as incorporation of P33 from ATP into biotinylated-cofilin substrate by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed