BDBM50057003 4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e][1,2]thiazine-3-carboxylic acid (4-methyl-thiazol-2-yl)-amide::CHEMBL367864

SMILES CN1C(C(=O)Nc2nc(C)cs2)=C(O)c2ccccc2S1(=O)=O

InChI Key InChIKey=ZGNRKLLCRYGEIK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057003   

TargetProstaglandin G/H synthase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057003(4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6...)
Affinity DataIC50:  830nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 2 activity as measured by PGE-2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50057003(4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda*6...)
Affinity DataIC50:  6.76E+3nMAssay Description:Concentration of drug that causes a 50% decrease in the maximal inhibition of Prostaglandin G/H synthase 1 activity as measured by PGE2 production('+...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed