BDBM50064248 (1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid::CHEMBL296054

SMILES N[C@]1(C[C@@H]2C[C@H]1[C@H]2C(O)=O)C(O)=O

InChI Key InChIKey=JCGJEPFYMOHIDP-RGDLXGNYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50064248   

TargetMetabotropic glutamate receptor 2(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  330nMAssay Description:Compound was tested for the inhibition of metabotropic glutamate receptor 2 (mGluR2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  2.30E+4nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50064248((1S,2S,4S,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dic...)
Affinity DataEC50:  5.30E+3nMAssay Description:Compound was tested for the inhibition of Metabotropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed