BDBM50064321 2-isopropylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d][1,3]oxazin-4-one::CHEMBL49333

SMILES CC(C)Nc1nc2sc3CCCCc3c2c(=O)o1

InChI Key InChIKey=LPEJWKTWRFIRAS-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50064321   

TargetNeutrophil elastase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064321(2-isopropylamino-5,6,7,8-tetrahydro-benzo[4,5]thie...)
Affinity DataKi:  145nM Kon:  0.000201M-1s-1 Koff:  1.39E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt-activated lipase(Bovine)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50064321(2-isopropylamino-5,6,7,8-tetrahydro-benzo[4,5]thie...)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAcetylcholinesterase(Electric eel)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50064321(2-isopropylamino-5,6,7,8-tetrahydro-benzo[4,5]thie...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity AChE from Electrophorus electricus using ATCh substrate and DTNB by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed