BDBM50067887 3-NITROPHENYLBORONIC ACID::3-Nitro-phenyl-1-dihydroxyborane::3-Nitrophenyl boronic acid::Boronic acid derivative::CHEMBL20945::m-nitophenyl boronic acid

SMILES O[B-](=[OH+])c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=ZNRGSYUVFVNSAW-UHFFFAOYSA-N

Data  7 KI  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50067887   

TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against E. coli AmpC beta-lactamase.More data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity of the compound towards AmpC beta-lactamase binding site from Escherichia coliMore data for this Ligand-Target Pair
TargetSubtilisin Carlsberg(Bacillus licheniformis)
TBA

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  8.00E+3nMAssay Description:Competitive inhibition of Subtilisin Carlsberg enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  1.50E+4nMAssay Description:Competitive inhibition of Subtilisin BL M222C-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition of Subtilisin BL wild type enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubtilisin BL(Bacillus lentus)
TBA

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  3.80E+4nMAssay Description:Competitive inhibition of Subtilisin BL M222S-mutated enzyme from B. lentusMore data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase TEM(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataKi:  1.21E+5nMAssay Description:Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTrypsin-2(Human)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was tested for its specificity against beta-trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bovine)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataIC50: >2.00E+5nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM50067887(3-NITROPHENYLBORONIC ACID | 3-Nitro-phenyl-1-dihyd...)
Affinity DataIC50:  5.00E+3nMAssay Description:Compound was tested for its specificity against AmpC beta-lactamaseMore data for this Ligand-Target Pair