BDBM50068745 CHEMBL78499::N-(3,4-Dimethyl-isoxazol-5-yl)-2-fluoro-benzenesulfonamide

SMILES Cc1noc(NS(=O)(=O)c2ccccc2F)c1C

InChI Key InChIKey=RZRSCFPIKIODFH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50068745   

TargetEndothelin-1 receptor(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50068745(CHEMBL78499 | N-(3,4-Dimethyl-isoxazol-5-yl)-2-flu...)
Affinity DataKi:  4.70E+3nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50068745(CHEMBL78499 | N-(3,4-Dimethyl-isoxazol-5-yl)-2-flu...)
Affinity DataIC50:  770nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article