BDBM50076135 (2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoic acid::(S)-2-{4-[(1H-Imidazol-4-ylmethyl)-amino]-2-naphthalen-1-yl-benzoylamino}-4-methyl-pentanoic acid::CHEMBL26246

SMILES CC(C)C[C@H](NC(=O)c1ccc(NCc2cnc[nH]2)cc1-c1cccc2ccccc12)C(O)=O

InChI Key InChIKey=ODTFPKNIFYMEHP-VWLOTQADSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076135   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50:  5.40E+3nMAssay Description:In vitro inhibition of [3H]-FPP incorporation into H-Ras-CVLS by Farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibition of [3H]-GGPP incorporation into H-Ras-CVLL by Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50076135((2S)-2-(4-((1H-imidazol-4-yl)methylamino)-2-(napht...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed