BDBM50076309 (4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydro-6-oxa-1-aza-chrysen-3-one::CHEMBL284475

SMILES C[C@@H]1C(=O)C(C)(C)Nc2ccc3-c4ccccc4O[C@@H](c4ccccc4)c3c12

InChI Key InChIKey=QXSLSLICSJPAFZ-WNSKOXEYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50076309   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076309((4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydr...)
Affinity DataKi:  6.60nMAssay Description:Compound was evaluated for its binding affinity against baculovirus expressed Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076309((4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydr...)
Affinity DataKi:  249nMAssay Description:Binding affinity against baculovirus expressed human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076309((4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydr...)
Affinity DataKi:  732nMAssay Description:Binding affinity against baculovirus expressed human androgen receptor (hAR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076309((4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydr...)
Affinity DataEC50:  10nMAssay Description:Compound was tested for agonistic activity by cotransfection assay against human Progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076309((4S,5S)-2,2,4-Trimethyl-5-phenyl-1,2,4,5-tetrahydr...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity by cotransfection assay against human Progesterone receptor in T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed