BDBM50077940 3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-propoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL66762

SMILES COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCCN(C)C)c1)c1ccc2OCOc2c1

InChI Key InChIKey=XGNOQSFKTHSFOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077940   

TargetEndothelin-1 receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077940(3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-prop...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin A receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50077940(3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-prop...)
Affinity DataIC50: >250nMAssay Description:Inhibition of [125I]-ET-1 binding to recombinant human Endothelin B receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed