BDBM50080082 3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one::CHEMBL69998::Firocoxib

SMILES CC1(C)OC(=O)C(OCC2CC2)=C1c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FULAPETWGIGNMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080082   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity against Human Prostaglandin G/H synthase 1 in U937 Microsome COX-1 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080082(3-Cyclopropylmethoxy-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed