BDBM50083623 (3R,8R)-8-Phenethyl-2-phenyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane

SMILES Cc1ccc(cc1)[C@@H]1CC2CCC(C1c1ccccc1)N2CCc1ccccc1

InChI Key InChIKey=VRZKLUWXHSBNPD-NWSXLFDYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083623   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083623((3R,8R)-8-Phenethyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]mazindol from cocaine binding site on Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083623((3R,8R)-8-Phenethyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [3H]dopamine uptake at striatal nerve endings by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50083623((3R,8R)-8-Phenethyl-2-phenyl-3-p-tolyl-8-aza-bicyc...)
Affinity DataKi:  180nMAssay Description:Inhibition of [3H]5-HT uptake at striatal nerve endings by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed